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NFT: The rats of Manhattan and the diseases they spread

Greg from LI : 10/15/2014 2:58 pm
Interesting article on the paucity of research into the diseases carried by animals, and a recent study conducted by researchers at Columbia on the diseases they found in rats in Manhattan. I have to say, though, that reading this:

Quote:
Although the scientists examined just 133 rats, they found plenty of pathogens. Some caused food-borne illnesses. Others, like Seoul hantavirus, had never before been found in New York. Others were altogether new to science.


reminded me of a classic Simpsons episode:

Quote:
We knew that Krusty-Os contained spider eggs, but the hantavirus? Ho-ho-ho, that really came outta left field!


Anyway, worth reading.
Link - ( New Window )
Those damn Koreans...  
RC02XX : 10/15/2014 3:00 pm : link
trying to spread disease to wipe out the US...you sure Ebola wasn't actually created by Koreans?
I want all flights from Korea banned, like YESTERDAY!  
Greg from LI : 10/15/2014 3:22 pm : link
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I wouldn't say paucity...  
Bill L : 10/15/2014 3:28 pm : link
Zoonotic diseases are very hot right now and Ebola is only going to make the spotlight shine brighter.

More than rats, bats harbor more viruses than anything. In fact, fruit bats are likely the central reservoir for Ebola in Africa where they urn ate, dedicate around foodstuff and are actually consumed by people there. They are gourmet food in Asia as well.

The bats in a North America are radically different than those in other places where the virus discovery work has been done, but who knows how many viruses they hold.

didn't bats bite pigs and cause the epidemic in that movie  
Del Shofner : 10/15/2014 3:33 pm : link
"Contagion"? Not that anything like that could happen in real life ...

"At the CDC, Dr. Ally Hextall (Jennifer Ehle) finds that the virus is a mix of genetic material from pig and bat viruses. Investigations into cures via treatment protocols or vaccines initially stall as scientists can't find a cell culture in which to grow the newly identified Meningoencephalitis Virus One (MEV-1). UCSF professor Dr. Ian Sussman (Elliott Gould) violates orders from Cheever (relayed through Hextall) to destroy his samples and identifies a usable line of bat cells. Hextall then uses this breakthrough to begin to investigate possible vaccines. The virus turns out to spread via fomites with a basic reproduction number of two; that is, each patient infects two more patients on average — increasing to four after the virus mutates, with projections of one in twelve of the population catching the virus and a 25-30% mortality rate for those infected."
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Jim in Fairfax : 10/15/2014 3:36 pm : link
Research is actually hampered because of the lack of available tools  
Bill L : 10/15/2014 3:42 pm : link
There really aren't any bat cell lines. At least until very recently. One research group in Australia ( now in Singapore) has successfully created bat cell lines from different tissues but they are only just being characterized. There are no cell lines originating from bats in our hemisphere. Neither are there antibodies that react with bat cells which could be used to identify different cell types or used for assays and research, etc. There is only one monoclonal anti-bat antibody and that reacts specifically with antibodies in bats themselves. I hope that's useful for developing serological assays and probing bat immunity to viruses (because I made it myself lol). We're also trying to make cell lines from M American bats but no success yet.
RE: .  
BMac : 10/15/2014 4:10 pm : link
In comment 11922022 Jim in Fairfax said:
Quote:


A fan of Ratatouille, I see.
Rats  
Bill L : 10/15/2014 7:36 pm : link
It's cool,they discover new life though, regardless of any disease implications
...  
Boyle : 10/15/2014 8:04 pm : link
Mice are a huge reason for the spread of Bed bugs in NYC. They get it from one apartment and then spread it to the next.

These things should really be dealt with by the city.
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