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NFT: First Wuhan Coronavirus Patient Identified in the USA

GMAN4LIFE : 1/21/2020 2:06 pm
Quote:
A person in Washington State is infected with the Wuhan coronavirus, the first confirmed case in the United States of a mysterious respiratory infection that has killed at least six people and sickened hundreds more in Asia.

The man is a resident of Snohomish County, Wash., who experienced symptoms after returning from a trip to the region around Wuhan, China, where the outbreak began. He was hospitalized with pneumonia last week, and infection with the coronavirus was confirmed on Monday afternoon.

Local officials declined to identify the patient, who was said to be quite ill.

News of the first case in the United States comes amid growing evidence that the virus spreads from person to person, although it is not clear how easily.

The outbreak, which began in a seafood and poultry market in Wuhan, a city of 11 million, is spreading: Patients have been identified in Beijing, Shanghai and Shenzhen, as well as Taiwan, Japan, Thailand and South Korea.



story - ( New Window )
Scares the shit out of me  
BigBlueDownTheShore : 1/21/2020 2:17 pm : link
They need to out law these meat markets where they butcher all sorts of animals in the same area without disinfecting their areas. That’s why they always start in China.
I was in Wuhan 3 times last year.  
11 to 89 : 1/21/2020 2:19 pm : link
Last visit was in July. I had a trip scheduled there in December that got cancelled due to budget constraints. Pretty happy about that cancellation.
I work in Queens and there is this Asian market by me.  
robbieballs2003 : 1/21/2020 3:15 pm : link
I went into it a couple of years back and I walked by the meat section. They had raw chicken on ice open to the public. So, you could just go up, grab your own raw chicken, and put it in your own bag.
Throw him in the Pacific.  
Dave in Hoboken : 1/21/2020 3:22 pm : link
.
I don't know anything about this coranavirus  
Bill L : 1/21/2020 3:36 pm : link
but I would guess that it's not open air markets per se but that either the market location or farms raising livestock are close enough to arboreal areas or wildlife in general that spillover (either into livestock or human feed) occurs.
RE: Throw him in the Pacific.  
Mike from SI : 1/21/2020 3:37 pm : link
In comment 14788427 Dave in Hoboken said:
Quote:
.


And get all the fish sick, who will then infect us? No thanks.
Is this virus even that dangerous?  
Section331 : 1/21/2020 3:42 pm : link
From what I've seen, it is no worse than a standard flu virus.
RE: Is this virus even that dangerous?  
Bill L : 1/21/2020 3:45 pm : link
In comment 14788455 Section331 said:
Quote:
From what I've seen, it is no worse than a standard flu virus.


Well, in this country the standard flu has so far killed over 2100 people in this country, so...
Wow....  
Ryan : 1/21/2020 3:46 pm : link
Flashbacks from SARS.......which if I recall led to the death of Randy's monkey more than 15 years ago.
RE: RE: Is this virus even that dangerous?  
Bill L : 1/21/2020 3:47 pm : link
In comment 14788461 Bill L said:
Quote:
In comment 14788455 Section331 said:


Quote:


From what I've seen, it is no worse than a standard flu virus.



Well, in this country the standard flu has so far killed over 2100 people, so...


and that's with a vigorous vaccination program (caveat being that there is a mismatch for at least one one of the strains, so efficacy is down a bit this year.
RE: RE: Throw him in the Pacific.  
Dave in Hoboken : 1/21/2020 3:48 pm : link
In comment 14788450 Mike from SI said:
Quote:
In comment 14788427 Dave in Hoboken said:


Quote:


.



And get all the fish sick, who will then infect us? No thanks.


Well played.
RE: I don't know anything about this coranavirus  
BlueLou'sBack : 1/21/2020 5:06 pm : link
In comment 14788445 Bill L said:
Quote:
but I would guess that it's not open air markets per se but that either the market location or farms raising livestock are close enough to arboreal areas or wildlife in general that spillover (either into livestock or human feed) occurs.


What does feed have to do with it?

It's a RESPIRATORY virus.

Do you know something that hasn't been reported or you jus' makin' shit up?
RE: RE: I don't know anything about this coranavirus  
Bill L : 1/21/2020 5:35 pm : link
In comment 14788588 BlueLou'sBack said:
Quote:
In comment 14788445 Bill L said:


Quote:


but I would guess that it's not open air markets per se but that either the market location or farms raising livestock are close enough to arboreal areas or wildlife in general that spillover (either into livestock or human feed) occurs.



What does feed have to do with it?

It's a RESPIRATORY virus.

Do you know something that hasn't been reported or you jus' makin' shit up?

As I said, I don’t know anything about this particular virus, so from that perspective you can take it as me making shit up. However it’s not out of the realm of possibility or without precedent that an aerosol from a wild animal (rodent or bat, etc) adheres to feed where livestock stick their faces and inhale. Also, we don’t necessarily know the route of transmission, regardless of where the virus ends up. Just making the point that it’s not necessarily because of an open air market.
Bill L - I seriously wanted to know if you'd read anything  
BlueLou'sBack : 1/21/2020 5:45 pm : link
new about transmission.

Coronaviruses are known (generally) to be relatively weak transmitters, and the last report I read was that epidemiological evidence now points to human to human transmissions. (Via skin contact, coughing through the air, etc.) Haven't read how viable the virus is on an inorganic surface, so blaming lack of bacterial (and viral) disinfection on the surface of butcher blocks or cutting boards may be way premature.

More than that, I have read nothing.
RE: Wow....  
Jay in Toronto : 1/21/2020 6:47 pm : link
In comment 14788465 Ryan said:
Quote:
Flashbacks from SARS.......which if I recall led to the death of Randy's monkey more than 15 years ago.


Lots of innocent people died. I knew some.
RE: RE: RE: I don't know anything about this coranavirus  
BigBlueDownTheShore : 1/21/2020 7:08 pm : link
In comment 14788634 Bill L said:
Quote:
In comment 14788588 BlueLou'sBack said:


Quote:


In comment 14788445 Bill L said:


Quote:


but I would guess that it's not open air markets per se but that either the market location or farms raising livestock are close enough to arboreal areas or wildlife in general that spillover (either into livestock or human feed) occurs.



What does feed have to do with it?

It's a RESPIRATORY virus.

Do you know something that hasn't been reported or you jus' makin' shit up?


As I said, I don’t know anything about this particular virus, so from that perspective you can take it as me making shit up. However it’s not out of the realm of possibility or without precedent that an aerosol from a wild animal (rodent or bat, etc) adheres to feed where livestock stick their faces and inhale. Also, we don’t necessarily know the route of transmission, regardless of where the virus ends up. Just making the point that it’s not necessarily because of an open air market.


Those markets are breeding grounds for these viruses because of how unsanitary they are. The SARS virus was linked directly too one. It’s harder for this to happen on the farms themselves, but in those markets blood, feces, bacteria, etc. are passed very easily because of where they are.

The reason these things start in China is fascinating...  
Tom in Kzoo : 1/21/2020 10:20 pm : link
and misinderstood.

It's not hygiene per se. It's the unique intersection of factors there that make it so. Avian influenza(and influenza in general) all start in China because:

1. High density of people-increased communicability of everything.

2.Pigs and fowl and humans together: many small farms, people have a few chickens, and pigs often.

2. Warm,subtropical weather where influenza is present year round, not just seasonally.

3. This means admixture of human and avian influenza in pigs-which uniquely can harbor both- and therefore can lead to unique genomic reassortments in the pig of 2 different virus strains that would not otherwise be possible. Unique,novel strains no human has ever seen.

Coronavirus may be transmissable across species line in same way- think of SARS (Civet cats, China) and MERS (camels, Middle East).
RE: The reason these things start in China is fascinating...  
Bill L : 1/21/2020 10:34 pm : link
In comment 14789029 Tom in Kzoo said:
Quote:
and misinderstood.

It's not hygiene per se. It's the unique intersection of factors there that make it so. Avian influenza(and influenza in general) all start in China because:

1. High density of people-increased communicability of everything.

2.Pigs and fowl and humans together: many small farms, people have a few chickens, and pigs often.

2. Warm,subtropical weather where influenza is present year round, not just seasonally.

3. This means admixture of human and avian influenza in pigs-which uniquely can harbor both- and therefore can lead to unique genomic reassortments in the pig of 2 different virus strains that would not otherwise be possible. Unique,novel strains no human has ever seen.

Coronavirus may be transmissable across species line in same way- think of SARS (Civet cats, China) and MERS (camels, Middle East).

Completely agree. I was just trying to make the point, inarticulately I guess, that there’s lots of intersections in places like this. A lot of new viruses do have wild fauna as reservoir hosts and there is spillover into domestic animals and humans.

This is totally unrelated, but I was at a conference a couple years ago and someone gave a talk on Nipah virus. They showed some time lapse night video of a tree in some Indian village where they set barrels in the tree to harvest some sort of liquid from a tap. I can’t recall what it was but think something like maple syrup. Whatever it was, it’s harvested and drunk by livestock and people. Anyway, the video showed bats coming in at night to take a drink and sometime urinate in the barrel. Anyway, bats are a reservoir for Nipah (why the talk was there) and it can spillover into pigs and humans.

Also saw a talk at the meeting by a Chinese researcher (who identified a SARS-like sequence in bats, suggesting an origin, where she had a picture of a big wok full of bats being stir-fried as a (relatively?) common dish in parts of China.
Didn't know they nailed Nipah's epidemiology that well. Interesting.  
Tom in Kzoo : 1/21/2020 10:45 pm : link
I wonder if that sap is what in indian cooking when dried is called asfoetida- a resin added to may dishes in powdered for- with a distinctive flavor.

Are you a researcher Bill ?
What exactly sets this illness apart from the standard flu?  
Knineteen : 1/21/2020 11:05 pm : link
or cold?

How can the CDC definitely identify the first case?
Fuck, they can't even positively identify strep in my children and that shit has been around for decades.
RE: Didn't know they nailed Nipah's epidemiology that well. Interesting.  
Bill L : 1/21/2020 11:09 pm : link
In comment 14789042 Tom in Kzoo said:
Quote:
I wonder if that sap is what in indian cooking when dried is called asfoetida- a resin added to may dishes in powdered for- with a distinctive flavor.

Are you a researcher Bill ?


Lots of hats now. Some basic research and also diagnostic lab. Mice, bats, and humans, oh my.
coronavirus  
Tom in Kzoo : 1/21/2020 11:14 pm : link

ID via nasal swab pcr that are already commonly used (if it cross reacts to standard coronavirus) or if it doesn't, novel specially made pcr or antigen testing . Growing the virus in the lab allows for gene sequencing to identify and use specific DNA/RNA sequences of the virus to then make antibodies or amplify those gene sequences for ID in lab via pcr technology.

Strep is different in that many things cause the same syndrome of pharyngitis and strep can be present in the throat and not be the cause-colonization- so that clinical setting matters alot to determine if the test of + has meaning.
Bill, that's cool.  
Tom in Kzoo : 1/21/2020 11:16 pm : link
We wrestle with RIDP panel not changing physician behavior in terms of antibiotic prescribing even paradoxically when viruses are isolated- so we dropped the test as each costs $500.
Our virology lab which does the molecular testing is top notch  
Bill L : 1/21/2020 11:26 pm : link
Our lab is a serology for infectious disease, mostly vector-borne or vpd. Both labs did the bulk of testing for NYS for both the zika and measles outbreaks. I’m sure our virology lab is setting up to test for this coronavirus as we speak.
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