Man is this second dose kicking my ass. Got the shot yesterday.
Was fine up until bed time. Couldnt sleep right, woke up with body aches and a mild fever. My wife felt the same way but my parents however feel perfectly fine. Another friend of mine ,around the same age, also feels the same. Almost exactly the same.
Any reasoning to older people feeling fine after the second shot but the semi younger crowd feeling like shit?
Quote:
I was texting with my buddy who works for Northwell today. He was saying there’s a lot of evidence now that is suggesting people who are having reactions after the first shot likely had covid already. It’s because their bodies are already recognizing the proteins in the vaccine. Seems to make some sense.
How do you explain the placebo group in the trials where the same side effects in slightly lesser percentage occurred?
Also, the symptoms people have are the same as in the trials and everyone in the trial was known to have no prior COVID.
Feel better!
but a bad night's sleep. Had a bad night's sleep for a couple of nights after the first shot. First shot gave me a hot spot (painful if touched or slept on) on my arm for a couple of days.
Quote:
I was texting with my buddy who works for Northwell today. He was saying there’s a lot of evidence now that is suggesting people who are having reactions after the first shot likely had covid already. It’s because their bodies are already recognizing the proteins in the vaccine. Seems to make some sense.
How do you explain the placebo group in the trials where the same side effects in slightly lesser percentage occurred?
No idea
Quote:
I was texting with my buddy who works for Northwell today. He was saying there’s a lot of evidence now that is suggesting people who are having reactions after the first shot likely had covid already. It’s because their bodies are already recognizing the proteins in the vaccine. Seems to make some sense.
How do you explain the placebo group in the trials where the same side effects in slightly lesser percentage occurred?
Did the study take into account which subjects had allergies and which did not? There are some discussions about having allergies might mean you have a more active immune system, which would be a good thing. Breaking down the type of allergy might also be useful.
Do Allergies Protect Us? - ( New Window )
In particular, the immune system is deeply remodeled during aging. Several mechanisms of both innate and adaptive immunity undergo age-related changes, configuring the so-called immunosenescence. Many aspects of immune function decline with aging, while others become more active....
This immune dysregulation provides the background for the development of the increased susceptibility to infections and autoimmune diseases, neoplasias, metabolic diseases, osteoporosis, neurological disorders, as well as to allergic inflammation.
There is a whole section on respiratory tract modifications which is interesting as well. The changes from ageing might be a factor in why Covid is so deadly to populations 70 and older (though I suspect damage caused by smoking and air quality is likely a major factor here).