If you have type II diabetes as I do, this post may interest you. Let me start out by saying that this is only anecdotal evidence. It may not apply to your particular body chemistry.
I am on a keto-friendly diet. I keep my blood sugar under control with pills and a low carb diet. I test my blood sugar frequently.
The other day I was using those little yellow packets of Splenda (sucralose + 95% dextrose (D-glucose) and maltodextrin by volume) to sweeten my yogurt and it drove my blood sugar up by 20 points or more AND it stayed up. I don't know if the culprit was the sucralose, or the dextrose & maltodextrin, but several hundred yellow packets of Splenda went into the garbage.